>Homo sapiens_PDE5A(ENSP_347046)
MERAGPSFGQQRQQQQPQQQKQQQRDQDSVEAWLDDHWDFTFSYFVRKATREMVNAWFAE
RVHTIPVCKEGIRGHTESCSCPLQQSPRADNSAPGTPTRKISASEFDRPLRPIVVKDSEG
TVSFLSDSEKKEQMPLTPPRFDHDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLI
SADRYSLFLVCEDSSNDKFLISRLFDVAEGSTLEEVSNNCIRLEWNKGIVGHVAALGEPL
NIKDAYEDPRFNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDE
KDFAAYLAFCGIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIIS
FMQVQKCTIFIVDEDCSDSFSSVFHMECEELEKSSDTLTREHDANKINYMYAQYVKNTME
PLNIPDVSKDKRFPWTTENTGNVNQQCIRSLLCTPIKNGKKNKVIGVCQLVNKMEENTGK
VKPFNRNDEQFLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETREL
QSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWIL
SVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGV
NNSYIQRSEHPLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAI
LATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAE
LVATEFFDQGDRERKELNIEPTDLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCF
PLLDGCRKNRQKWQALAEQQEKMLINGESGQAKRN

>Macaca mulatta_PDE5A(ENSMMUP_9576)
MERAGLSFGRQRQQQQPQQQKQQQRDQDSVEAWLDDHWDFTFSYFVRKATREMVNAWFAE
RVHTIPVCKEGIRGHTESCSCPLQQSPRADNSAPGTPTRKISASEFDRPLRPIVVKDSEG
TVSFLSDSEKKEQMPLTPPRFDHDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLI
SADRYSLFLVCEDSSNDKFLISRLFDVAEGSTLEEASNNCIRLEWNKGIVGHVAALGEPL
NIKDAYEDPRFNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDE
KDFAAYLAFCGIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIIS
FMQVQKCTIFIVDEDCSDSFSSVFHMECEELEKSSDMLTREHDTNKINYMYAQYVKNTME
PLNIPDVSKDKRFPWTTENTGNVSQQCIRSLLCTPIKNGKKNKVIGVCQLVNKMEENTGK
VKPFNRNDEQFLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETREL
QSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWIL
SVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGV
NNSYIQRSEHPLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAI
LATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAE
LVASEFFDQGDRERKELNIEPTDLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCF
PLLDGCRKNRQKWQALAEQQEKMLINGESGQAKRN

>Mus musculus_PDE5A(ENSMUSP_69011)
MERAGPNSVRSQQQRDPDWVEAWLDDHRDFTFSYFIRKATRDMVNAWFSERVHNIPVCKE
GIRAHTESCSCSLQQSPHADNTTPGAPARKISASEFDRPLRPIVVKDSEGTVSFLSDSGK
KEQMPLTPPRFDSDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLISADRYSLFLV
CEDSSKDKFLISRLFDVAEGSTLEEASNNCIRLEWNKGIVGHVAAFGEPLNIKDAYEDPR
FNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDEKDFAAYLAFC
GIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIF
IVDEDCPDSFSRVFHMECEEVGKPSDPLTREQDANKINYMYAQYVKNTMEPLNIPDVTKD
KRFPWTNENMGHVNTPCIGSLLCTPIKNGKKNKVIGVCQLVNKMEENTGKIKAFNQNDEQ
FLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQALSAAVVPS
AQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNV
AYHNWRHAFNTAQCMFAALKAGKIQNKLTDLETLALLIAALSHDLDHRGVNNSYIQRSEH
PLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIDEYKTTLKIIKQAILATDLALYIK
RRGEFFELIRKNQFSFEDPLQKELFLAMLMTACDLSAITKPWPIQQRIAELVAAEFFDQG
DRERKELNMEPADLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCLPLLDGCRKNR
QKWQALAEQQEKMLLNGESSQGKRD

>Felis catus_PDE5A(ENSFCAP_9620)
MVNAWFAERVHTIPVCKEGIRSHTESCSCPSQQSPRADSSAPGTPTRKISASEFDRPLRP
IVVKDSEGTVSFLSDSEKKEQMPLTPPRFDNDEGDQCSRLLELVKDISSHLDVTALCHKI
FLHIHGLISADRYSLFLVCEDSSNDKFLISRLFDVAEGSTLEEASNNCIRLEWNKGIVGH
VAAFGEPLNIKDAYEDPRFNAEVDQITGYRTQSILCMPIKNHREEVVGVAQAINKRSGNG
GTFTEKDEKDFAAYLAFCGIVLHNAQLYETSLLENKRNQAKVLLDLASLIFEEQQSLEVI
LKKIAATIISFMQVQKCTIFIVDEDCSDSFSSVFHMECEELEKSSDTLTRERDANRINYM
YAQYVKNTMEPLNIPDVSKDKRFPWTNENTGSVSQQFIRSLLCTPIKNGKKNKVIGVCQL
VNKMEENTGKVKPFNRNDEQFLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHA
SAAEEETRELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQM
KHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLETLALLIAA
LSHDLDHRGVNNSYIQRSEHPLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYK
TTLKIIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITK
PWPIQQRIAELVATEFFDQGDRERKELNIEPADLMNREKKNKIPSMQVGFIDAICLQLYE
ALTHVSEDCFPLLDGCRKNRQKWQALAEQQEKMLINGESSQAKRN

>Gallus gallus_PDE5A(ENSGALP_19524)
MERSCHPSPEQEAVEAWLDDHCDFTRSYFVRKATREMVNAWFAERVHTIPVCKEGTKSQS
ESCACQQLACSENTNSGTPARKISASEFDRPLRPIFVKDSVGAVSFLSGSEKKEQMPLQS
PRTGTSAGDRCSRLLELVKDISSHLDVTALCHKIFLHIHELIAADRYSLFLVCEDSSNEK
FLVSRLFDVAEGSTLEEASNNCIRLEWNKGIVGHVAAIGQPLNIKNAYEDPRFNAEVDQI
TGYKTQSILCMPIKNHREEVVGVAQAINKKSGTGGTFTEQDEKDFAAYLAFCGIVLHNAQ
LYETSLLENRRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQRCTIFIVDEDCTD
SFSSVFHMEAEELEDSAENQKRDCDTNKINYMYAQYVKNTMEPLNIPDVCKDRRFPWTTD
SAESVSQHIKSLLCTPIKNGKKNKVIGVCQLVNKMEENSGKIKAFNRNDEQFLEAFVIFC
GLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEESRELQVTAAAVVPSAQSLNLTDF
NFSDFELSDFETTLCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAF
NTAQCMFAALKSGKIQSKLTDLETLALLIATLSHDLDHRGVNNSYIQRSEHPLAQLYCHS
IMEHHHFDQCLMILNSPGNQILSSLSIEEYKATLKMIKQAILATDLALYIKRRGEFFELL
RKKQFNWEDPMQKELFLAMLMTACDLSAITKPWPVQQRIAELVATEFFDQGDKERKELNI
EPTDLMNREKKNKIPSMQVGFIDAVCLQLYEALTHVSEACYPLLDGCRKNRQKWQSLAEQ
QEKNLINGESNQAKRN

>Anolis carolinensis_PDE5A(ENSACAP_13103)
KAWILLFWDFLLNLLRERRGREMVNAWFSERVHTIPVCKEGTKTHSETCSCSTLQTTRSE
NTNSTPPARKISASEFDRPLRPIVVKDSIGTVSFLSDSEKKEQMPLQSRTLRTDAGDQCT
RLLELVKDISSHLDVTALCHKIFLHIHELIAADRYSLFLVCEDSSNEKFLVSRLFDVAEG
TTLEEASNNCIRLEWNKGIVGHVAALGQPLNIKDAYEDPRFNAEVDQITGYKTQSILCMP
IKNHREEVVGVAQAINKKSGGGGTFTEQDEKDFSAYLAFCGIVLHNAQLYETSLLENRRN
QVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQQCTIFIVDEDCSDSYSSVFHMEFEE
LEDSNETHKRDYDTNQINYMYAQYVKNTMEPLNIPNIRQDKRFPWTPFNVNNVNAQKVCP
KQLLLTTEKELGEKNETPNDPGVCQLANKMEENSCKIKAFNRNDEQFLEAFVIFCGLGIQ
NTQMYEAVERAMAKQMVTLEVLSYHASAADEEARELQVTAAAVVPSAQSLGLTDFYFSDF
ELSDMETSLCTIRMFTDLNLVQNFQMKHEVLCRWILSVRKNYRKNVAYHNWRHAFNTAQC
MFAALKSGKIQNKLTDTEVLSLLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCHSIMEHH
HFDQCLMILNTPGNQILSGLSVEEYKATVKMIKQAILATDLALYIKRRGEFFDLLRKKQF
NLEDPYQKELFLAMLMTACDLSAITKPWPVQQRKTQIAELVAAEFFDQGDKERQELNIEP
TDLMNREKKNKIPSMQVGFIDAICLQLYEALTHISEACYPLLEGCRKNRQKWQALAEQQE
NNLINGESNQPKRN

>Xenopus tropicalis_PDE5A(ENSXETP_8757)
QVVGVAQAINKKSGSNGTFTDQDEKDFAAYLAFCGIVLHNAQLYETSLLENRRNQVLLDL
ATLIFEEQQSLEVILKKIAATILSFMQAQRCTIFIVDEDSPDTFSSVFHMESDELEESAD
AVKREYDVSKMNYMYAQYVANTMEAINIPDICKDTRFPWTNGNEEKNFKHIQSLLCSPIK
NAKKNKVIGVCQLVNKVDENSGKIKAFNKNDEQFLEAFAIFCGLGIQNTQMFEVVERAMA
KQMVTLEILSYHASAAEEETMELQVTAGAIVPSAQSLKLTEFYFSDFELSDMETTLATSR
MFTDLNLVQTFQMKYEKTLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALRTGKIQG
KLNDLEILALMIATLSHDLDHRGVNNSFIQRSEHPLAQLYCHSIMENHHFDQCLMILNSQ
GNQILSGLSVQDYKTVLKMIKQAILATDLALYIKRRSDFFELVNKKKFKWDDPSQKELFL
AMLMTACDLSAITKPWPVQQRIAELVASEFYDQGDKERRELNIEPIDLMNREKKDKIPSM
QVGFIDAVCLELYEALTQISESCYPLLDGCQRNRQMWQILAEQQEKNLVNGAKSQPEVKC
NMD

>Danio rerio_PDE5A(ENSDARP_68115)
MEVYPSDSERMMEAWLDDNLEFAHSYFVRKASREMVNAWFAERVHSIQPSREPSKAVPEP
VTAVHSLGPTDVVPSSSPAPSTPTRKISASEFDRPLRPIVVKDAEGSFTFLSDTERVQMP
LPPSQRPGSDNGTDEGGGIRDRGNGDRCARLLELVRDVSSHLDLTALCHKIFLHTHELIA
ADRYSLFLVGEDSSNRKFLVSRLFDVAEGSTLEESSNSGIRLEWNKGIVGYVAATGQPLN
IKNAYEDSRFNAEVDQITGYKTQSILCLPIKNHRDEVVGVAQAINKKCGENSTFTEQDEK
DFSSYLAFSGIVLHNAQLYETSQLENRRNQVLLDLASLIFEEQQSLEVLLRKTVATILSF
MQAQECTVFISDRETANTFASVFHMEYEEIAGSTDFPNRECDVNKINYMYAQYVKNTMET
LNITDTTKDQLFSWTSEDPQSTNCQIKSLLCTPIRNGKKDKVIGVCQLVNKMDEASGEVK
AFNRNDEQFLEAFAVFCGLGIQNTQMYEAVERAMAKQEVTLEVLSYHASAAEEETRALQV
TAAATIPSAQSLRLMDYSFSDFDLTDAETTQATIRMFVDLKLVQNFQIKYKSLCQWILSV
KKNYRKNVVYHNWRHAFNTSQCMFAVLKSGRVQNNLSDLETLALMIATLSHDLDHRGVNN
SYIKRSDHPLAQLYCHSTMEHHHFDQCLMILNSPGNQILSGLSLDEYKATLKMIEKAILA
TDLAVYMKKRTEFFELAKNSQFEWEDDCHRDLLRSMLMTACDISAITKPWPVQKKIAELV
ATEFFEQGDKERRELNIEPIDLMNREKQDKIPSMQVSFIDAICTQLYEALTGISEFCSPL
LEGCRKNRQNWKILAEQGEEAALLNGEL

>Takifugu rubripes_PDE5A(ENSTRUP_25606)
ESERMEAWLDDHLEFTRSYFIRKASREMVNAWFAERVHSIHPSAPKENPPQHPRTQQSSA
DSAVTAPSPVPGTPTRKISASEFDRPLRPIVVKDAEGSLTFLSDADRETVPVRAAAMGEG
GGVHVGGCDEAGSWCGRDRCARLLELVKEVSSHLDVTALCHKIFLHINELIAADRYSLFL
VGEDSSNRKFLVSRLFDVAEGSTVEESSSSCIRLEWNKGIVGHVAATGQPLNIKNAYEDS
RFNAEVDLITGYKTHSILCLPIKNHRDEVVGVAQAINKKSGDDAAFTDQDEKDFSAYLAF
SGIVLHNAQLYETSQLENRRNQVLLDLASLIFEEQQCLKVLLRKFAGTILSFMQAQACTV
FIADEDSMNSFSSVFHMEYEELGEVLDVPKRDCDVSQINYMYAQYVKNTMQTLNIADVTK
DQRFPWTGENPDHTNDQIKSLLCTPIRNGKKDKVIGVCQLVNKMDEASDSVKAFNRNDEQ
FLEAFAIFCGLGIQNTQMYETVERAMAKQEVTLEVLSYHATASEEESRELQVTVVATVPS
AQSLRLLDFSFSDFELSDTETTLATIRMFVDLNLVQNFQMKYMNLCRWVLSVKKNYRKSV
AYHNWRHAFNTAQSMFALLKSGRLQNNLNDLEVLALMIATLSHDLDHRGVNNSYIQRSDH
PLAQLYCHSTMEHHHFDHCLMILNSPGNQILSSLSLDEYKSTLKMIERAILATDLALYMK
RRGEFFELTKNSQFVWEDEQHRDLLRSMLMTACDISAITKPWPVQQRIAELVATEFFEQG
DKERRELNIEPSDLMNREKKDKIPSMQVSFIDAICTQLYETLAGMSEYCSPLLEGCQKNR
QQWKHLAEECEKGLVNG

>Oryzias latipes_PDE5A(ENSORLP_25741)
SLCQWILSVKKNYRKSVAYHNWRHAFNTAQCMFALLKSGRLQNNLSDLEILALMIATLSH
DLDHRGVNNSYIQRSEHPLAQLYCHSTMEHHHFDQCLMILNTPGNQILSGLSLDEYKATL
KMIEKAILATDLALYMKKREDFFELTKNNQFVWVDEHHRDLLRSMLMTACDISAITKPWP
VQKRVAELVATEFFEQGDKERRELNIEPTDLMNREKRDKIPSMQVSFIDAICIQLYETLA
GLLEHCSPLLEGCQKNRQHWKRLAEDCEK